E45 Itch Relief Cream contains an anti-itch ingredient, lauromacrogols, which treats and soothes the itching caused by eczema, dermatitis, pruritus and scaling skin conditions.Formulated with urea, a moisturiser found naturally within the skin, E45 Itch Relief Cream is non-greasy, moisturising and can soothe the skin and leave it feeling calm and comfortable.